Exam map · click any node
Hematopoiesis
One stem cell. Two master routes. Tap a cell to reveal its dominant signals, function, and exam anchors.
HSC → mature blood
MYELOIDLYMPHOIDGROWTH FACTOR LABELS
Hematopoietic
stem cell
stem cell
Common myeloid
progenitor (CMP)
progenitor (CMP)
Common lymphoid
progenitor (CLP)
progenitor (CLP)
SCF · FLT3-L
self-renewal
self-renewal
Megakaryocyte–
erythroid progenitor
erythroid progenitor
Granulocyte–
monocyte progenitor
monocyte progenitor
Myeloid / DC
progenitor
progenitor
IL-3 · GM-CSF
IL-3 · GM-CSF
Erythrocyte
Megakaryocyte
→ platelets
→ platelets
EPO
TPO · IL-11
Neutrophil
Eosinophil
Basophil
G-CSF
IL-5
IL-3 · IL-4
Monocyte
→ macrophage
→ macrophage
Myeloid
dendritic cell
dendritic cell
M-CSF
FLT3-L · GM-CSF
B-cell
progenitor
progenitor
T-cell
progenitor
progenitor
NK-cell
progenitor
progenitor
IL-7
IL-15
B lymphocyte
→ plasma cell
→ plasma cell
T lymphocyte
(CD4 / CD8)
(CD4 / CD8)
NK cell
IL-7 · BAFF
IL-7 · IL-2
IL-15
Mast cell
SCF · IL-3
Selected: overview
Start at the HSC
Tap any node in the map. The dominant exam-associated growth factor is printed beside each branch; the detail panel adds what the cell does and the classic testable association.
Self-renewal: SCFEarly support: FLT3-LTwo master progenitors: CMP + CLP
Growth-factor rules
Exam trap: these are dominant associations, not exclusive switches. Hematopoiesis is a cytokine network: SCF/FLT3-L support early progenitors, while lineage-selective signals bias expansion and maturation.